Since ECF osmolarity will not be lower than ICF's, fluid from ECF will expand the ICF compartment and further lower the ECF fluid volume. What kind of shift in body fluid compartments would you see with Aldosterone or Renal Deficiency? In this situation, excess NaCl will be excreted in the Urine, therefore ECF would lose both volume and osmolarity. Overall there will be a Hypertonic Volume Contraction. Thus fluid will fall from ICF into ECF to follow the solute. This is causing the ECF to lose water but hold on to its sodium ions. That means you are losing more water than solute. Relative to ECF, how does the osmolarity of sweat differ? How would someone who is sweating a lot change their body fluid compartments. Since its Isosmotic, ICF levels would not change, only ECF would decrease. What kind of shift in body fluid compartments would you see in Diarrhea? Diarrhea leads to isosmotic volume contraction because the fluid that is lost to diarrhea is relatively the same as ECF fluid. What is the Gibbs Donnan effect? This effect predicts that the plasma cation levels will be higher than that of interstitial fluid. It should average around 45% (48% in males and 42% in females). ![]() What is hematocrit? Hematocrit is the persentage of blood volume occupied by red blood cells. ![]() What are the major cations and anions of the ECF? Sodium is the major cation of the ECF while Cl and Bicarb are the major anions. What contents make up the ECF component of total body water? ECF is divided into Interstitial Fluid (3/4 ECF) and Plasma (1/4 ECF) What are the major cations and anions of the ICF? Potassium and Magnesium are the main cations in the ICF while proteins and organic phosphates serve as the major anions of the ICF. Women have lower percentages of water because they have higher percentages of adipose tissue. Water content of the body correlates inversely to what content? Water correlates inversely with fat content. ECF and ICF are what fractions of total body water? ECF is 2/3 total body water. ![]() What is the 60-40-20 rule? Water is 60% of total body weight. What is the function of the Vasa Recta? To serve as osmotic exchangers for the production of concentrated urine. The Juxtamedullary Nephrons has the peritubular capillaries have a specialization called the Vasa Recta that follow allong the loops of Henle. How is blood flow different in the Superficial Nephrons than the Juxtamedullary Nephrons? Superficial Nephrons have peritubular capillaries that branch off the efferent arterioles to deliver nutrients to the epithelial cells.
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